2xcf

X-ray diffraction
2.48Å resolution

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-111143 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidase S29 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 198 amino acids
Theoretical weight: 21 KDa
Source organism: Hepacivirus hominis
Expression system: Escherichia coli
UniProt:
  • Canonical: C1KHN2 (Residues: 1-180; Coverage: 99%)
Sequence domains: Hepatitis C virus NS3 protease
Structure domains:
Hepatitis C virus Non-structural protein NS4a domain-containing protein Chains: C, D
Molecule details ›
Chains: C, D
Length: 23 amino acids
Theoretical weight: 2.39 KDa
Source organism: Hepacivirus hominis
Expression system: Not provided
UniProt:
  • Canonical: C9WU77 (Residues: 21-39; Coverage: 35%)
Sequence domains: Hepatitis C virus non-structural protein NS4a

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: R32
Unit cell:
a: 225.889Å b: 225.889Å c: 75.196Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.194 0.226
Expression systems:
  • Escherichia coli
  • Not provided