› 2xll

X-ray diffraction
2.3Å resolution

The crystal structure of bilirubin oxidase from Myrothecium verrucaria

Released:
DOI: 10.2210/pdb2xll/pdb
PDB entry 2xll coloured by chain, front view.
PDB entry 2xll coloured by chain, side view.
PDB entry 2xll coloured by chain, top view.
Source organism: Albifimbria verrucaria
Primary publication:
Bilirubin oxidase from Myrothecium verrucaria: X-ray determination of the complete crystal structure and a rational surface modification for enhanced electrocatalytic O2 reduction.
Cracknell JA, McNamara TP, Lowe ED, Blanford CF
Dalton Trans 40 6668-75 (2011)
PMID: 21544308

Function and Biology Details

Reaction catalysed: 
2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171387 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Bilirubin oxidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 534 amino acids
Theoretical weight: 60.01 KDa
Source organism: Albifimbria verrucaria
UniProt:
  • Canonical: Q12737 (Residues: 39-572; Coverage: 97%)
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand CU 16 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P1
Unit cell:
a: 52.793Å b: 83.602Å c: 143.148Å
α: 89.98° β: 89.89° γ: 89.9°
R-values:
R R work R free
0.172 0.17 0.216

Quick links

Citations

5 review citations

Three-dimensional structures of laccases.
Hakulinen et al. (2015)
4 more

10 mentions without citation

Direct enzymatic bioelectrocatalysis: differentiating between myth and reality.
Milton et al. (2017)
9 more