› 3a82

X-ray diffraction
1.75Å resolution

Crystal Structure of Trypsin complexed with pre-synthesized (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid

Released:
DOI: 10.2210/pdb3a82/pdb
PDB entry 3a82 coloured by chain, front view.
PDB entry 3a82 coloured by chain, side view.
PDB entry 3a82 coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Yamane J, Yao M, Tanaka I

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133319 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

4 bound ligands:
Ligand CA 1 x CA
Ligand SO4 2 x SO4
Ligand GOL 1 x GOL
Ligand O09 1 x O09
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 54.203Å b: 58.281Å c: 66.815Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.152 0.179

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