› 3bbz

X-ray diffraction
2.1Å resolution

Structure of the nucleocapsid-binding domain from the mumps virus phosphoprotein

Released:
DOI: 10.2210/pdb3bbz/pdb
PDB entry 3bbz coloured by chain, front view.
PDB entry 3bbz coloured by chain, side view.
PDB entry 3bbz coloured by chain, top view.
Source organism: Mumps orthorubulavirus
Primary publication:
Structure of the nucleocapsid-binding domain from the mumps virus polymerase; an example of protein folding induced by crystallization.
Kingston RL, Gay LS, Baase WS, Matthews BW
J Mol Biol 379 719-31 (2008)
PMID: 18468621

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-191573 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 49 amino acids
Theoretical weight: 5.46 KDa
Source organism: Mumps orthorubulavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9J4L6 (Residues: 343-391; Coverage: 13%)
Gene name: P
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

2 bound ligands:
Ligand BR 2 x BR
Ligand FMT 6 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1, SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 23.992Å b: 55.485Å c: 60.019Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.19 0.241
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Structural disorder within paramyxovirus nucleoproteins and phosphoproteins.
Habchi et al. (2012)
9 more

4 mentions without citation

The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics.
Cox et al. (2015)
3 more