› 3bop

X-ray diffraction
3Å resolution

Structure of mouse beta-neurexin 2D4

Released:
DOI: 10.2210/pdb3bop/pdb
PDB entry 3bop coloured by chain, front view.
PDB entry 3bop coloured by chain, side view.
PDB entry 3bop coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structures of beta-neurexin 1 and beta-neurexin 2 ectodomains and dynamics of splice insertion sequence 4.
Koehnke J, Jin X, Trbovic N, Katsamba PS, Brasch J, Ahlsen G, Scheiffele P, Honig B, Palmer AG, Shapiro L
Structure 16 410-21 (2008)
PMID: 18334216

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Laminin G domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 175 amino acids
Theoretical weight: 19.04 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q3TQ54 (Residues: 87-260; Coverage: 57%)
Sequence domains: Laminin G domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: C2
Unit cell:
a: 95.485Å b: 96.983Å c: 62.584Å
α: 90° β: 105.98° γ: 90°
R-values:
R R work R free
0.215 0.211 0.289
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Neuroligins and neurexins link synaptic function to cognitive disease.
Südhof TC. (2008)
4 more

6 mentions without citation

Neurexins - versatile molecular platforms in the synaptic cleft.
Rudenko G. (2019)
5 more