› 3cq0

X-ray diffraction
1.9Å resolution

Crystal Structure of TAL2_YEAST

Released:
DOI: 10.2210/pdb3cq0/pdb
PDB entry 3cq0 coloured by chain, front view.
PDB entry 3cq0 coloured by chain, side view.
PDB entry 3cq0 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae.
Huang H, Rong H, Li X, Tong S, Zhu Z, Niu L, Teng M
Proteins 73 1076-81 (2008)
PMID: 18831051

Function and Biology Details

Reaction catalysed: 
Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156742 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transaldolase NQM1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 339 amino acids
Theoretical weight: 38.1 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P53228 (Residues: 1-333; Coverage: 100%)
Gene names: NQM1, YGR043C
Sequence domains: Transaldolase/Fructose-6-phosphate aldolase
Structure domains: Aldolase class I

Ligands and Environments

3 bound ligands:
Ligand EDO 17 x EDO
Ligand PG4 2 x PG4
Ligand GOL 14 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: I212121
Unit cell:
a: 85.027Å b: 113.461Å c: 158.917Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.215
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Transaldolase: from biochemistry to human disease.
Samland et al. (2009)
11 other articles