› 3fl6

X-ray diffraction
1.17Å resolution

Influence of the incorporation of a cyclohexenyl nucleic acid (CeNA) residue onto the sequence d(GCGTGCG)/d(CGCACGC)

Released:
DOI: 10.2210/pdb3fl6/pdb
PDB entry 3fl6 coloured by chain, front view.
PDB entry 3fl6 coloured by chain, side view.
PDB entry 3fl6 coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA.
Robeyns K, Herdewijn P, Van Meervelt L
Artif DNA PNA XNA 1 2-8 (2010)
PMID: 21687521

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116248 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*GP*CP*GP*(XTR)P*GP*CP*G)-3' Chains: A, C
Molecule details ›
Chains: A, C
Length: 7 nucleotides
Theoretical weight: 2.16 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*CP*GP*CP*AP*CP*GP*C)-3' Chains: B, D
Molecule details ›
Chains: B, D
Length: 7 nucleotides
Theoretical weight: 2.08 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NCO 7 x NCO
1 modified residue:
Ligand XTR 2 x XTR

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 25.72Å b: 33.57Å c: 81.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 not available not available
Expression system: Not provided

Quick links

Citations

5 citation in other articles

The crystal structure of the CeNA:RNA hybrid ce(GCGTAGCG):r(CGCUACGC).
Ovaere et al. (2011)
4 more

1 mention without citation

Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA.
Robeyns et al. (2010)