› 3g7l

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140878 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Chromo domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.38 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli
UniProt:
  • Canonical: Q10103 (Residues: 15-75; Coverage: 6%)
Gene names: SPAC18G6.02c, chp1
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Histone H3.1/H3.2 Chain: P
Molecule details ›
Chain: P
Length: 16 amino acids
Theoretical weight: 1.77 KDa
Source organism: Schizosaccharomyces pombe 972h-
Expression system: Not provided
UniProt:
  • Canonical: P09988 (Residues: 2-17; Coverage: 12%)
Gene names: SPAC1834.04, SPBC8D2.04, hht1, hht2, pi060

Ligands and Environments

2 bound ligands:
Ligand ACY 1 x ACY
Ligand ZN 4 x ZN
1 modified residue:
Ligand M3L 1 x M3L

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P43212
Unit cell:
a: 41.56Å b: 41.56Å c: 87.38Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.196 0.237
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

29 review citations

RNAi-dependent formation of heterochromatin and its diverse functions.
Grewal SI. (2010)
28 more

7 mentions without citation

Breakers and amplifiers in chromatin circuitry: acetylation and ubiquitination control the heterochromatin machinery.
Bailey et al. (2021)
6 more