› 3gvh

X-ray diffraction
2.3Å resolution

Crystal structure of Lactate/malate dehydrogenase from Brucella melitensis

Released:
DOI: 10.2210/pdb3gvh/pdb
PDB entry 3gvh coloured by chain, front view.
PDB entry 3gvh coloured by chain, side view.
PDB entry 3gvh coloured by chain, top view.
Source organism: Brucella abortus 2308
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
(S)-malate + NAD(+) = oxaloacetate + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174166 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Malate dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 324 amino acids
Theoretical weight: 34.04 KDa
Source organism: Brucella abortus 2308
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2YLR9 (Residues: 1-320; Coverage: 100%)
Gene names: BAB1_1927, mdh
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 4 x NAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 91.75Å b: 114.35Å c: 148.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.174 0.218
Expression system: Escherichia coli

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