› 3h7r

X-ray diffraction
1.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131331 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldo-keto reductase family 4 member C8 Chain: A
Molecule details ›
Chain: A
Length: 331 amino acids
Theoretical weight: 36.9 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: O80944 (Residues: 1-311; Coverage: 100%)
Gene names: AKR4C8, At2g37760, F13M22, T8P21.6
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain

Ligands and Environments

3 bound ligands:
Ligand NAP 1 x NAP
Ligand ACT 1 x ACT
Ligand EDO 12 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: C2
Unit cell:
a: 173.431Å b: 39.909Å c: 47.223Å
α: 90° β: 99.63° γ: 90°
R-values:
R R work R free
0.156 0.155 0.183
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Methylglyoxal: An Emerging Signaling Molecule in Plant Abiotic Stress Responses and Tolerance.
Hoque et al. (2016)
6 more

2 mentions without citation

Focus on Nitric Oxide Homeostasis: Direct and Indirect Enzymatic Regulation of Protein Denitrosation Reactions in Plants.
Treffon et al. (2022)
1 more