Function and Biology Details
Reaction catalysed:
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- DNA topoisomerase I
- DNA topoisomerase I, catalytic core, eukaryotic-type
- DNA topoisomerase I, N-terminal domain superfamily
- DNA topoisomerase I, active site
- DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type
- DNA breaking-rejoining enzyme, catalytic core
- DNA topoisomerase I, N-terminal, viral
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
DNA topoisomerase 1 and DNA (preferred)
PDBe Complex ID:
PDB-CPX-116403 (preferred)
Entry contents:
1 distinct polypeptide molecule
3 distinct DNA molecules
3 distinct DNA molecules
Macromolecules (4 distinct):
DNA topoisomerase 1
Molecule details ›
P32989
