Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 300-mer (preferred)
PDBe Complex ID:
PDB-CPX-240202 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Capsid protein VP1
Molecule details ›
Chain: 1
Length: 235 amino acids
Theoretical weight: 26.56 KDa
Source organism: Human poliovirus 1 Mahoney
Expression system: Not provided
UniProt:
Length: 235 amino acids
Theoretical weight: 26.56 KDa
Source organism: Human poliovirus 1 Mahoney
Expression system: Not provided
UniProt:
- Canonical:
P03300 (Residues: 647-881; Coverage: 11%)
Capsid protein VP2
Molecule details ›
Chain: 2
Length: 14 amino acids
Theoretical weight: 1.52 KDa
Source organism: Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B)
Expression system: Not provided
UniProt:
Length: 14 amino acids
Theoretical weight: 1.52 KDa
Source organism: Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B)
Expression system: Not provided
UniProt:
- Canonical: P03302 (Residues: 83-96; Coverage: 1%)
Genome polyprotein
Molecule details ›
Chain: 3
Length: 231 amino acids
Theoretical weight: 25.78 KDa
Source organism: Poliovirus 1
Expression system: Not provided
UniProt:
Length: 231 amino acids
Theoretical weight: 25.78 KDa
Source organism: Poliovirus 1
Expression system: Not provided
UniProt:
- Canonical: Q9E8Z2 (Residues: 342-572; Coverage: 11%)
Capsid protein VP2
Molecule details ›
Chain: 4
Length: 245 amino acids
Theoretical weight: 27.18 KDa
Source organism: Human poliovirus 1 Mahoney
Expression system: Not provided
UniProt:
Length: 245 amino acids
Theoretical weight: 27.18 KDa
Source organism: Human poliovirus 1 Mahoney
Expression system: Not provided
UniProt:
- Canonical: P03300 (Residues: 97-341; Coverage: 11%)
