› 3kfg

X-ray diffraction
1.43Å resolution

Major mouse urinary protein IV complexed with 2-heptanone

Released:
DOI: 10.2210/pdb3kfg/pdb
PDB entry 3kfg coloured by chain, front view.
PDB entry 3kfg coloured by chain, side view.
PDB entry 3kfg coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Perez-Miller S, Zou Q, Novotny MV, Hurley TD
Protein Sci 19 1469-79 (2010)
PMID: 20509168

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145883 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major urinary protein 4 Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.85 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P11590 (Residues: 17-178; Coverage: 100%)
Gene name: Mup4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

3 bound ligands:
Ligand CL 2 x CL
Ligand 2EH 1 x 2EH
Ligand HTX 1 x HTX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P212121
Unit cell:
a: 47.697Å b: 53.743Å c: 60.946Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.203
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Vomeronasal organ and human pheromones.
Trotier D. (2011)
1 more

2 mentions without citation

High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Perez-Miller et al. (2010)
1 more