› 3kvd

X-ray diffraction
2Å resolution

Crystal structure of the Neisseria meningitidis Factor H binding protein, fHbp (GNA1870) at 2.0 A resolution

Released:
DOI: 10.2210/pdb3kvd/pdb
PDB entry 3kvd coloured by chain, front view.
PDB entry 3kvd coloured by chain, side view.
PDB entry 3kvd coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Cendron L, Veggi D, Girardi E, Zanotti G
Acta Crystallogr Sect F Struct Biol Cryst Commun 67 531-5 (2011)
PMID: 21543855

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180250 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipoprotein GNA1870 Chain: D
Molecule details ›
Chain: D
Length: 242 amino acids
Theoretical weight: 25.97 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6QCC2 (Residues: 33-274; Coverage: 95%)
Gene names: fhbp, gna1870
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P3121
Unit cell:
a: 83.097Å b: 83.097Å c: 71.301Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.227 0.25
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen.
Seib et al. (2015)
2 more

12 mentions without citation

Vaccines against Meningococcal Diseases.
Pizza et al. (2020)
11 more