› 3kzu

X-ray diffraction
1.75Å resolution

Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Brucella melitensis

Released:
DOI: 10.2210/pdb3kzu/pdb
PDB entry 3kzu coloured by chain, front view.
PDB entry 3kzu coloured by chain, side view.
PDB entry 3kzu coloured by chain, top view.
Source organism: Brucella melitensis
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
A (Z)-hexadec-9-enoyl-[acyl-carrier protein] + a malonyl-[acyl-carrier protein] = a (Z)-3-oxooctadec-11-enoyl-[acyl-carrier protein] + CO(2) + an [acyl-carrier protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-[acyl-carrier-protein] synthase 2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 428 amino acids
Theoretical weight: 45.17 KDa
Source organism: Brucella melitensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8YFP7 (Residues: 1-420; Coverage: 100%)
Gene name: BMEI1473
Sequence domains:
Structure domains: Peroxisomal Thiolase; Chain A, domain 1

Ligands and Environments

2 bound ligands:
Ligand EDO 3 x EDO
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 118.02Å b: 62.32Å c: 177.72Å
α: 90° β: 109.18° γ: 90°
R-values:
R R work R free
0.15 0.148 0.181
Expression system: Escherichia coli

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