› 3lcx

X-ray diffraction
1.98Å resolution

L-KDO aldolase

Released:
DOI: 10.2210/pdb3lcx/pdb
PDB entry 3lcx coloured by chain, front view.
PDB entry 3lcx coloured by chain, side view.
PDB entry 3lcx coloured by chain, top view.
Source organism: Escherichia coli K-12
Entry authors: Chou C-Y, Huang K-F, Wang AH-J, Ko T-P

Function and Biology Details

Reaction catalysed: 
Aceneneuramate = N-acetyl-D-mannosamine + pyruvate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-acetylneuraminate lyase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 319 amino acids
Theoretical weight: 35.13 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A6L4 (Residues: 1-297; Coverage: 100%)
Gene names: JW3194, b3225, nanA, npl
Sequence domains: Dihydrodipicolinate synthetase family
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
Ligand SO4 8 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P3221
Unit cell:
a: 120.805Å b: 120.805Å c: 196.291Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.233 0.279
Expression system: Escherichia coli

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