› 3maw

X-ray diffraction
3.5Å resolution

Structure of the Newcastle disease virus F protein in the post-fusion conformation

Released:
DOI: 10.2210/pdb3maw/pdb
PDB entry 3maw coloured by chain, front view.
PDB entry 3maw coloured by chain, side view.
PDB entry 3maw coloured by chain, top view.
Source organism: Newcastle disease virus (STRAIN AUSTRALIA-VICTORIA/32)
Primary publication:
Structure of the Newcastle disease virus F protein in the post-fusion conformation.
Swanson K, Wen X, Leser GP, Paterson RG, Lamb RA, Jardetzky TS
Virology 402 372-9 (2010)
PMID: 20439109

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146267 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Fusion glycoprotein F1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 483 amino acids
Theoretical weight: 51.16 KDa
Source organism: Newcastle disease virus (STRAIN AUSTRALIA-VICTORIA/32)
Expression system: Not provided
UniProt:
  • Canonical: P12572 (Residues: 32-499; Coverage: 90%)
Gene name: F
Sequence domains: Fusion glycoprotein F0
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NDG 2 x NDG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B
Spacegroup: R3
Unit cell:
a: 83.253Å b: 83.253Å c: 461.406Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.263 0.261 0.294
Expression system: Not provided

Quick links

Citations

13 review citations

Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years.
Collins et al. (2011)
12 more

9 mentions without citation

Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry.
Bose et al. (2015)
8 more