3me2

X-ray diffraction
2.8Å resolution

Crystal structure of mouse RANKL-RANK complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-128661 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor necrosis factor ligand superfamily member 11, soluble form Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.06 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35235 (Residues: 158-316; Coverage: 50%)
Gene names: Opgl, Rankl, Tnfsf11, Trance
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Tumor necrosis factor receptor superfamily member 11A Chain: R
Molecule details ›
Chain: R
Length: 216 amino acids
Theoretical weight: 24.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35305 (Residues: 26-210; Coverage: 30%)
Gene names: Rank, Tnfrsf11a
Sequence domains:
Structure domains: Tumor Necrosis Factor Receptor, subunit A, domain 2

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4, ESRF BEAMLINE ID23-2
Spacegroup: P63
Unit cell:
a: 121.225Å b: 121.225Å c: 94.995Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.175 0.174 0.205
Expression system: Escherichia coli