› 3ogn

X-ray diffraction
1.3Å resolution

Crystal Structure of an Odorant-binding Protein from the Southern House Mosquito Complexed with an Oviposition Pheromone

Released:
DOI: 10.2210/pdb3ogn/pdb
PDB entry 3ogn coloured by chain, front view.
PDB entry 3ogn coloured by chain, side view.
PDB entry 3ogn coloured by chain, top view.
Source organism: Culex quinquefasciatus
Primary publication:
Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone.
Mao Y, Xu X, Xu W, Ishida Y, Leal WS, Ames JB, Clardy J
Proc Natl Acad Sci U S A 107 19102-7 (2010)
PMID: 20956299

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186131 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Odorant-binding protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 14.4 KDa
Source organism: Culex quinquefasciatus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8T6I2 (Residues: 26-149; Coverage: 99%)
Gene names: 6039292, CpipJ_CPIJ007604
Sequence domains: PBP/GOBP family
Structure domains: Pheromone/general odorant binding protein domain

Ligands and Environments

2 bound ligands:
Ligand 3OG 2 x 3OG
Ligand MG 4 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 35.915Å b: 107.31Å c: 38.529Å
α: 90° β: 100.38° γ: 90°
R-values:
R R work R free
0.134 0.132 0.174
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Odorant reception in insects: roles of receptors, binding proteins, and degrading enzymes.
Leal WS. (2013)
4 more

25 mentions without citation

Recent insights about pyrrolidine core skeletons in pharmacology.
Poyraz et al. (2023)
24 more