› 3olz

X-ray diffraction
2.75Å resolution

Crystal structure of the GluK3 (GluR7) ATD dimer at 2.75 Angstrom resolution

Released:
DOI: 10.2210/pdb3olz/pdb
PDB entry 3olz coloured by chain, front view.
PDB entry 3olz coloured by chain, side view.
PDB entry 3olz coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structures of the glutamate receptor ion channel GluK3 and GluK5 amino-terminal domains.
Kumar J, Mayer ML
J Mol Biol 404 680-96 (2010)
PMID: 20951142

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154592 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, kainate 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 398 amino acids
Theoretical weight: 45.35 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: P42264 (Residues: 32-423; Coverage: 44%)
Gene names: Glur7, Grik3
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:
Ligand NAG 5 x NAG
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P61
Unit cell:
a: 171.211Å b: 171.211Å c: 68.234Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.195 0.252
Expression system: Homo sapiens

Quick links

Citations

8 review citations

Functional insights from glutamate receptor ion channel structures.
Kumar et al. (2013)
7 more

5 mentions without citation

Emerging models of glutamate receptor ion channel structure and function.
Mayer ML. (2011)
4 more