Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
beta1-catenin - LEF1 complex (preferred)
PDBe Complex ID:
PDB-CPX-151067 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin beta-1
Molecule details ›
Chain: A
Length: 540 amino acids
Theoretical weight: 58.99 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
Length: 540 amino acids
Theoretical weight: 58.99 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q02248 (Residues: 134-671; Coverage: 69%)
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
Lymphoid enhancer-binding factor 1
Molecule details ›
Chain: B
Length: 67 amino acids
Theoretical weight: 7.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Structure domains: TCF3-CBD (Catenin binding domain)
Length: 67 amino acids
Theoretical weight: 7.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P27782 (Residues: 1-63; Coverage: 16%)
Structure domains: TCF3-CBD (Catenin binding domain)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-1
Spacegroup:
I422
Expression system: Escherichia coli
