› 3p1i

X-ray diffraction
2.1Å resolution

Ligand binding domain of human ephrin type-B receptor 3

Released:
DOI: 10.2210/pdb3p1i/pdb
PDB entry 3p1i coloured by chain, front view.
PDB entry 3p1i coloured by chain, side view.
PDB entry 3p1i coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Yermekbayeva L, Seitova A, Kania J, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157088 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-B receptor 3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 200 amino acids
Theoretical weight: 23.1 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P54753 (Residues: 39-211; Coverage: 18%)
Gene names: EPHB3, ETK2, HEK2, TYRO6
Sequence domains: Ephrin receptor ligand binding domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P43212
Unit cell:
a: 102.16Å b: 102.16Å c: 117.86Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.184 0.235
Expression system: Spodoptera frugiperda

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