3p38

X-ray diffraction
2.76Å resolution

Crystal structure of the NS1 effector domain W182A mutant from influenza A/Vietnam/1203/2004 (H5N1) virus

Released:
Entry authors: Chen S, Xiao YB, Bricogne G, Sharff AJ, Hilgenfeld R

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-112310 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 147 amino acids
Theoretical weight: 16.35 KDa
Source organism: Influenza A virus (A/environment/Viet Nam/1203/2004(H5N1))
Expression system: Escherichia coli
UniProt:
  • Canonical: D1LP63 (Residues: 73-215; Coverage: 67%)
Gene names: NS, NS1
Sequence domains: Influenza non-structural protein (NS1)
Structure domains: Influenza virus non-structural protein, effector domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P4322
Unit cell:
a: 78.785Å b: 78.785Å c: 186.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.231 0.271
Expression system: Escherichia coli