› 3pb3

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed: 
S-adenosyl-L-methionine + adenine(1408) in 16S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(1408) in 16S rRNA
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-108594 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
16S rRNA (adenine(1408)-N(1))-methyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 225 amino acids
Theoretical weight: 25.82 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: A8C927 (Residues: 1-219; Coverage: 100%)
Gene name: npmA
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments


Cofactor: Ligand SAH 2 x SAH
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P43
Unit cell:
a: 64.419Å b: 64.419Å c: 108.499Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.241
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Bioinformatics Tools and Benchmarks for Computational Docking and 3D Structure Prediction of RNA-Protein Complexes.
Nithin et al. (2018)
2 more

2 mentions without citation

Mechanisms of Resistance to Aminoglycoside Antibiotics: Overview and Perspectives.
Garneau-Tsodikova et al. (2016)
1 more