› 3phg

X-ray diffraction
1.57Å resolution

Crystal structure of the Shikimate 5-Dehydrogenase (aroE) from Helicobacter pylori

Released:
DOI: 10.2210/pdb3phg/pdb
PDB entry 3phg coloured by chain, front view.
PDB entry 3phg coloured by chain, side view.
PDB entry 3phg coloured by chain, top view.
Source organism: Helicobacter pylori 26695
Entry authors: Cheng WC, Lin SC, Wang WC

Function and Biology Details

Reaction catalysed: 
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157396 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Shikimate dehydrogenase (NADP(+)) Chains: A, B
Molecule details ›
Chains: A, B
Length: 269 amino acids
Theoretical weight: 30.14 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli
UniProt:
  • Canonical: P56119 (Residues: 1-263; Coverage: 100%)
Gene names: HP_1249, aroE
Sequence domains: Shikimate dehydrogenase substrate binding domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1, SPRING-8 BEAMLINE BL12B2
Spacegroup: P21
Unit cell:
a: 45.328Å b: 46.181Å c: 118.702Å
α: 90° β: 99.04° γ: 90°
R-values:
R R work R free
0.202 0.2 0.24
Expression system: Escherichia coli

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