3q82

X-ray diffraction
2.1Å resolution

Meropenem acylated BlaR1 sensor domain from Staphylococcus aureus

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-148358 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulatory protein BlaR1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 29.59 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P18357 (Residues: 332-368, 371-371, 373-583; Coverage: 43%)
Gene name: blaR1
Sequence domains: Penicillin binding protein transpeptidase domain
Structure domains: DD-peptidase/beta-lactamase superfamily

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 46.801Å b: 108.087Å c: 56.451Å
α: 90° β: 108.98° γ: 90°
R-values:
R R work R free
0.186 0.183 0.234
Expression system: Escherichia coli