› 3r5o

X-ray diffraction
2.6Å resolution

Crystal structure of the complex of bovine lactoperoxidase with 4-allyl-2-methoxyphenol at 2.6 A resolution

Released:
DOI: 10.2210/pdb3r5o/pdb
PDB entry 3r5o coloured by chain, front view.
PDB entry 3r5o coloured by chain, side view.
PDB entry 3r5o coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Pandey N, Singh AK, Singh RP, Sinha M, Kaur P, Sharma S, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160329 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lactoperoxidase Chain: A
Molecule details ›
Chain: A
Length: 595 amino acids
Theoretical weight: 67.85 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P80025 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase
Structure domains: Haem peroxidase domain superfamily, animal type

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
8 bound ligands:
Ligand CA 1 x CA
Ligand NAG 3 x NAG
Ligand IOD 10 x IOD
Ligand EUG 1 x EUG
Ligand MPD 1 x MPD
Ligand SCN 1 x SCN
Ligand EDO 2 x EDO
Ligand GOL 1 x GOL
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 54.008Å b: 80.047Å c: 75.676Å
α: 90° β: 102.98° γ: 90°
R-values:
R R work R free
0.219 0.219 0.245

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