› 3r9p

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + acetate = ADP + acetyl phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180972 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetate kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 391 amino acids
Theoretical weight: 41.66 KDa
Source organism: Mycobacterium avium subsp. paratuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q73T33 (Residues: 1-387; Coverage: 100%)
Gene names: MAP_3886, ackA
Sequence domains: Acetokinase family
Structure domains: Nucleotidyltransferase; domain 5

Ligands and Environments

3 bound ligands:
Ligand GOL 1 x GOL
Ligand EDO 1 x EDO
Ligand PGE 2 x PGE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 83.254Å b: 99.507Å c: 103.871Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.202
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Pleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer Cells.
Abu-Remaileh et al. (2015)
5 more

1 mention without citation

Investigation of pyrophosphate versus ATP substrate selection in the Entamoeba histolytica acetate kinase.
Dang et al. (2017)