› 3rwd

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-177756 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chains: A, D
Molecule details ›
Chains: A, D
Length: 276 amino acids
Theoretical weight: 32.03 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GJ77 (Residues: 24-299; Coverage: 80%)
Gene name: MHCI-B
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 99 amino acids
Theoretical weight: 11.66 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6V7J5 (Residues: 21-119; Coverage: 100%)
Gene name: B2M
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Protein Nef Chains: C, F
Molecule details ›
Chains: C, F
Length: 11 amino acids
Theoretical weight: 1.47 KDa
Source organism: Simian immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: Q5QGG3 (Residues: 165-175; Coverage: 4%)
Gene name: nef

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 45.219Å b: 69.025Å c: 81.001Å
α: 96.45° β: 88.79° γ: 89.94°
R-values:
R R work R free
0.23 0.228 0.277
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

3 review citations

Nonhuman primate models for HIV/AIDS vaccine development.
Sui et al. (2013)
2 more

1 mention without citation

Peptidomes and Structures Illustrate How SLA-I Micropolymorphism Influences the Preference of Binding Peptide Length.
Wei et al. (2022)