Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Vinculin and Talin-1 (preferred)
PDBe Complex ID:
PDB-CPX-148319 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin
Molecule details ›
Chains: A, B
Length: 253 amino acids
Theoretical weight: 28.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like
Length: 253 amino acids
Theoretical weight: 28.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P18206 (Residues: 1-252; Coverage: 22%)
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like
Talin-1
Molecule details ›
Chains: C, D
Length: 40 amino acids
Theoretical weight: 4.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Length: 40 amino acids
Theoretical weight: 4.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P26039 (Residues: 1512-1546; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 22-BM
Spacegroup:
P1
Expression system: Escherichia coli
