3t4x

X-ray diffraction
2.8Å resolution

Short chain dehydrogenase/reductase family oxidoreductase from Bacillus anthracis str. Ames Ancestor

Released:
Source organism: Bacillus anthracis
Entry authors: Filippova EV, Wawrzak Z, Skarina T, Edwards A, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-104745 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxidoreductase, short chain dehydrogenase/reductase family Chains: A, B
Molecule details ›
Chains: A, B
Length: 267 amino acids
Theoretical weight: 29.99 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A384KDK1 (Residues: 1-264; Coverage: 100%)
Gene name: GBAA_3440
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P42212
Unit cell:
a: 144.979Å b: 144.979Å c: 65.694Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.263
Expression system: Escherichia coli BL21(DE3)