3twy

X-ray diffraction
1.5Å resolution

RAT PKC C2 DOMAIN BOUND TO PB

Released:
Source organism: Rattus norvegicus
Primary publication:
Pb2+ as modulator of protein-membrane interactions.
J Am Chem Soc 133 10599-611 (2011)
PMID: 21615172

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-138745 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein kinase C alpha type Chain: A
Molecule details ›
Chain: A
Length: 137 amino acids
Theoretical weight: 16.05 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P05696 (Residues: 156-292; Coverage: 20%)
Gene names: Pkca, Prkca
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P3221
Unit cell:
a: 58.29Å b: 58.29Å c: 87.98Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.204 0.219
Expression system: Escherichia coli