Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
ATP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] = ADP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Signal transduction histidine kinase-related protein, C-terminal
- Histidine kinase/HSP90-like ATPase domain
- Histidine kinase/HSP90-like ATPase superfamily
- Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily
- Histidine kinase domain
- Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
- PDK/BCKDK protein kinase
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169496 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Branched-chain alpha-ketoacid dehydrogenase kinase
Molecule details ›
Chain: A
Length: 418 amino acids
Theoretical weight: 47.37 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 418 amino acids
Theoretical weight: 47.37 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q00972 (Residues: 1-412; Coverage: 100%)
Sequence domains:
- Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
- Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
