› 3ukv

X-ray diffraction
2.7Å resolution

Structure of the C-linker/CNBHD of zELK channels in P 1 21 1 space group, crystallized in the presence of cAMP

Released:
DOI: 10.2210/pdb3ukv/pdb
PDB entry 3ukv coloured by chain, front view.
PDB entry 3ukv coloured by chain, side view.
PDB entry 3ukv coloured by chain, top view.
Source organism: Danio rerio
Primary publication:
Structure of the carboxy-terminal region of a KCNH channel.
Brelidze TI, Carlson AE, Sankaran B, Zagotta WN
OpenAccess logo Nature 481 530-3 (2012)
PMID: 22230959

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108809 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel, subfamily H (eag-related), member 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 212 amino acids
Theoretical weight: 24.07 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A8WHX9 (Residues: 543-750; Coverage: 23%)
Gene name: kcnh3
Sequence domains: Cyclic nucleotide-binding domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 55.33Å b: 106.42Å c: 77.52Å
α: 90° β: 97.51° γ: 90°
R-values:
R R work R free
0.218 0.215 0.277
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

Intracellular pH in sperm physiology.
Nishigaki et al. (2014)
15 more

2 mentions without citation

Structure of the carboxy-terminal region of a KCNH channel.
Brelidze et al. (2012)
1 more