› 3v67

X-ray diffraction
2.3Å resolution

Periplasmic domain of Vibrio parahaemolyticus CpxA

Released:
DOI: 10.2210/pdb3v67/pdb
PDB entry 3v67 coloured by chain, front view.
PDB entry 3v67 coloured by chain, side view.
PDB entry 3v67 coloured by chain, top view.
Source organism: Vibrio parahaemolyticus
Primary publication:
The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA.
Kwon E, Kim DY, Ngo TD, Gross CA, Gross JD, Kim KK
Protein Sci 21 1334-43 (2012)
PMID: 22760860

Function and Biology Details

Reaction catalysed: 
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183339 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
histidine kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 16.23 KDa
Source organism: Vibrio parahaemolyticus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q87KW6 (Residues: 38-173; Coverage: 29%)
Gene name: VP2859
Sequence domains: Two-component sensor protein CpxA, periplasmic domain
Structure domains: Two-component sensor protein CpxA, periplasmic domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: R3
Unit cell:
a: 148.583Å b: 148.583Å c: 32.314Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.234 0.23 0.274
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Everything old is new again: an update on current research on the Cpx envelope stress response.
Raivio TL. (2014)
4 more

1 mention without citation

The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA.
Kwon et al. (2012)