Function and Biology Details
Reaction catalysed:
5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H(2)O = tetrahydrofolate + 2-dehydropantoate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo decamer (preferred)
Assembly name:
3-methyl-2-oxobutanoate hydroxymethyltransferase (preferred)
PDBe Complex ID:
PDB-CPX-173972 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-methyl-2-oxobutanoate hydroxymethyltransferase
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 275 amino acids
Theoretical weight: 29.05 KDa
Source organism: Burkholderia thailandensis E264
Expression system: Escherichia coli
UniProt:
Sequence domains: Ketopantoate hydroxymethyltransferase
Structure domains: Phosphoenolpyruvate-binding domains
Length: 275 amino acids
Theoretical weight: 29.05 KDa
Source organism: Burkholderia thailandensis E264
Expression system: Escherichia coli
UniProt:
- Canonical:
Q2SYZ1 (Residues: 1-271; Coverage: 100%)
Sequence domains: Ketopantoate hydroxymethyltransferase
Structure domains: Phosphoenolpyruvate-binding domains
