› 3wx9

X-ray diffraction
1.58Å resolution

Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA

Released:
DOI: 10.2210/pdb3wx9/pdb
PDB entry 3wx9 coloured by chain, front view.
PDB entry 3wx9 coloured by chain, side view.
PDB entry 3wx9 coloured by chain, top view.
Source organism: Pyrococcus horikoshii OT3
Entry authors: Okada K, Angkawidjaja C, Koga Y, Kanaya S

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminotransferase class I/classII large domain-containing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 448 amino acids
Theoretical weight: 51.16 KDa
Source organism: Pyrococcus horikoshii OT3
Expression system: Escherichia coli
UniProt:
  • Canonical: O57946 (Residues: 1-428; Coverage: 100%)
Gene name: PH0207
Sequence domains: Aminotransferase class I and II
Structure domains:

Ligands and Environments

6 bound ligands:
Ligand PMP 2 x PMP
Ligand AKG 2 x AKG
Ligand G9A 2 x G9A
Ligand 3EE 2 x 3EE
Ligand GLU 1 x GLU
Ligand KYA 1 x KYA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: C2
Unit cell:
a: 85.769Å b: 70.997Å c: 136.704Å
α: 90° β: 90.02° γ: 90°
R-values:
R R work R free
0.183 0.18 0.23
Expression system: Escherichia coli

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