Function and Biology Details
Reaction catalysed:
Aceneneuramate = N-acetyl-D-mannosamine + pyruvate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
homo tetramer (preferred)
Assembly name:
N-acetylneuraminate lyase (preferred)
PDBe Complex ID:
PDB-CPX-173512 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-acetylneuraminate lyase
Molecule details ›
Chains: A, B, C, D
Length: 298 amino acids
Theoretical weight: 33.75 KDa
Source organism: Staphylococcus aureus subsp. aureus NCTC 8325
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Dihydrodipicolinate synthetase family
Structure domains: Aldolase class I
Length: 298 amino acids
Theoretical weight: 33.75 KDa
Source organism: Staphylococcus aureus subsp. aureus NCTC 8325
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q2G160 (Residues: 2-293; Coverage: 100%)
Sequence domains: Dihydrodipicolinate synthetase family
Structure domains: Aldolase class I
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I04-1
Spacegroup:
P212121
Expression system: Escherichia coli BL21
