Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
E3 ubiquitin-protein ligase ZNRF3 (preferred)
PDBe Complex ID:
PDB-CPX-178281 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 ubiquitin-protein ligase ZNRF3
Molecule details ›
Chains: A, B, C
Length: 165 amino acids
Theoretical weight: 18.2 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
Sequence domains: ZNRF-3 Ectodomain
Structure domains: Glucose Oxidase; domain 1
Length: 165 amino acids
Theoretical weight: 18.2 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
- Canonical:
Q5SSZ7 (Residues: 53-205; Coverage: 18%)
Sequence domains: ZNRF-3 Ectodomain
Structure domains: Glucose Oxidase; domain 1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I24
Spacegroup:
C2
Expression system: Homo sapiens
