› 4cii

X-ray diffraction
2.15Å resolution

Crystal structure of N-terminally truncated Helicobacter pylori T4SS Protein CagL as domain swapped dimer

Released:
DOI: 10.2210/pdb4cii/pdb
PDB entry 4cii coloured by chain, front view.
PDB entry 4cii coloured by chain, side view.
PDB entry 4cii coloured by chain, top view.
Source organism: Helicobacter pylori 26695
Primary publication:
Structure of a three-dimensional domain-swapped dimer of the Helicobacter pylori type IV secretion system pilus protein CagL.
Barden S, Schomburg B, Conradi J, Backert S, Sewald N, Niemann HH
Acta Crystallogr D Biol Crystallogr 70 1391-400 (2014)
PMID: 24816107

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127739 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cag pathogenicity island protein (Cag18) Chain: A
Molecule details ›
Chain: A
Length: 225 amino acids
Theoretical weight: 25.75 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O25272 (Residues: 21-237; Coverage: 92%)
Gene name: HP_0539
Sequence domains: T4SS protein CagL

Ligands and Environments

1 bound ligand:
Ligand MRD 1 x MRD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P6522
Unit cell:
a: 61.841Å b: 61.841Å c: 244.499Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.198 0.237
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 citation in other articles

Genes required for assembly of pili associated with the Helicobacter pylori cag type IV secretion system.
Johnson et al. (2014)
10 more

14 mentions without citation

The Helicobacter pylori Cag Type IV Secretion System.
Cover et al. (2020)
13 more