Function and Biology Details
Reaction catalysed:
Exonucleolytic cleavage of poly(A) to 5'-AMP
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PAN2-PAN3 deadenylation complex (preferred)
PDBe Complex ID:
PDB-CPX-143024 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
PAN2-PAN3 deadenylation complex catalytic subunit pan2
Molecule details ›
Chains: A, C
Length: 354 amino acids
Theoretical weight: 39.52 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: PAN2 N-terminal
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Length: 354 amino acids
Theoretical weight: 39.52 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0C581 (Residues: 1-351; Coverage: 27%)
Sequence domains: PAN2 N-terminal
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
PAN2-PAN3 deadenylation complex subunit pan3
Molecule details ›
Chains: B, D
Length: 429 amino acids
Theoretical weight: 49.27 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Pan3 Pseudokinase domain
Structure domains:
Length: 429 amino acids
Theoretical weight: 49.27 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q7SDP4 (Residues: 234-656; Coverage: 65%)
Sequence domains: Pan3 Pseudokinase domain
Structure domains:
