› 4d6x

X-ray diffraction
2.11Å resolution

Crystal structure of the receiver domain of NtrX from Brucella abortus

Released:
DOI: 10.2210/pdb4d6x/pdb
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PDB entry 4d6x coloured by chain, front view.
PDB entry 4d6x coloured by chain, side view.
PDB entry 4d6x coloured by chain, top view.
Source organism: Brucella abortus
Primary publication:
Snapshots of Conformational Changes Shed Light into the NtrX Receiver Domain Signal Transduction Mechanism.
Fernández I, Otero LH, Klinke S, Carrica MDC, Goldbaum FA
J Mol Biol 427 3258-3272 (2015)
PMID: 26113057

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174177 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CbxX/CfqX superfamily:Chaperonin clpA/B:Response regulator receiver:Sigma-54 factor interaction domain:Helix-turn-helix, Fis Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 148 amino acids
Theoretical weight: 16.33 KDa
Source organism: Brucella abortus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q2YPW6 (Residues: 1-126; Coverage: 28%)
Gene name: BAB1_1138
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand IMD 3 x IMD
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 38.67Å b: 110.94Å c: 119.43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.213 0.219
Expression system: Escherichia coli BL21(DE3)

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Citations

3 review citations

Molecular Mechanisms of Two-Component Signal Transduction.
Zschiedrich et al. (2016)
2 more

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