› 4dq3

X-ray diffraction
2.1Å resolution

Bovine beta-lactoglobulin complex with oleic acid

Released:
DOI: 10.2210/pdb4dq3/pdb
PDB entry 4dq3 coloured by chain, front view.
PDB entry 4dq3 coloured by chain, side view.
PDB entry 4dq3 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Binding of 18-carbon unsaturated fatty acids to bovine β-lactoglobulin--structural and thermodynamic studies.
Loch JI, Bonarek P, Polit A, Riès D, Dziedzicka-Wasylewska M, Lewiński K
Int J Biol Macromol 57 226-31 (2013)
PMID: 23500663

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136153 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-lactoglobulin Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.3 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02754 (Residues: 17-178; Coverage: 100%)
Gene name: LGB
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

3 bound ligands:
Ligand OLA 1 x OLA
Ligand EOH 1 x EOH
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCE ULTRA
Spacegroup: P3221
Unit cell:
a: 53.46Å b: 53.46Å c: 111.57Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.237 0.231 0.289

Quick links

Citations

4 review citations

Bovine β-lactoglobulin/fatty acid complexes: binding, structural, and biological properties.
Le Maux et al. (2014)
3 more

3 mentions without citation

β-lactoglobulin's conformational requirements for ligand binding at the calyx and the dimer interphase: a flexible docking study.
Domínguez-Ramírez et al. (2013)
2 more