Function and Biology Details
Reaction catalysed:
(1a) L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- NIF system FeS cluster assembly, NifU, N-terminal
- Pyridoxal phosphate-dependent transferase, major domain
- Pyridoxal phosphate-dependent transferase, small domain
- Aminotransferase class V domain
- Pyridoxal phosphate-dependent transferase
- Cysteine desulfurase
- Cysteine desulfurase IscS
- NIF system FeS cluster assembly, NifU-like
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128159 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cysteine desulfurase IscS 2
Molecule details ›
Chains: A, B
Length: 382 amino acids
Theoretical weight: 41.89 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
Sequence domains: Aminotransferase class-V
Structure domains:
Length: 382 amino acids
Theoretical weight: 41.89 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
- Canonical:
O29689 (Residues: 1-382; Coverage: 100%)
Sequence domains: Aminotransferase class-V
Structure domains:
Iron-sulfur cluster assembly scaffold protein IscU 2
Molecule details ›
Chain: C
Length: 153 amino acids
Theoretical weight: 16.95 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
Sequence domains: NifU-like N terminal domain
Structure domains: Sufe protein. Chain: A
Length: 153 amino acids
Theoretical weight: 16.95 KDa
Source organism: Archaeoglobus fulgidus DSM 4304
Expression system: Escherichia coli
UniProt:
- Canonical: P0DMG2 (Residues: 1-153; Coverage: 100%)
Sequence domains: NifU-like N terminal domain
Structure domains: Sufe protein. Chain: A
