› 4enc

X-ray diffraction
2.27Å resolution

Crystal structure of fluoride riboswitch

Released:
DOI: 10.2210/pdb4enc/pdb
PDB entry 4enc coloured by chain, front view.
PDB entry 4enc coloured by chain, side view.
PDB entry 4enc coloured by chain, top view.
Source organism: Thermotoga petrophila
Primary publication:
Fluoride ion encapsulation by Mg2+ ions and phosphates in a fluoride riboswitch.
Ren A, Rajashankar KR, Patel DJ
OpenAccess logo Nature 486 85-9 (2012)
PMID: 22678284

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-250485 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
Fluoride riboswitch Chain: A
Molecule details ›
Chain: A
Length: 52 nucleotides
Theoretical weight: 16.78 KDa
Source organism: Thermotoga petrophila
Expression system: Not provided
Sequence domains: Fluoride riboswitch aptamer (crcB RNA motif)

Ligands and Environments

3 bound ligands:
Ligand MG 5 x MG
Ligand F 1 x F
Ligand K 1 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 57.01Å b: 75.223Å c: 42.905Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.252
Expression system: Not provided

Quick links

Citations

21 review citations

A decade of riboswitches.
Serganov et al. (2013)
20 more

23 mentions without citation

Structure and function of pseudoknots involved in gene expression control.
Peselis et al. (2014)
22 more