4enz

X-ray diffraction
2.6Å resolution

Structure of human ceruloplasmin at 2.6 A resolution

Released:

Function and Biology Details

Reactions catalysed:
2 glutathione + ROOH = glutathione disulfide + H(2)O + ROH
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132511 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ceruloplasmin Chain: A
Molecule details ›
Chain: A
Length: 1065 amino acids
Theoretical weight: 122.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00450 (Residues: 1-1065; Coverage: 100%)
Gene name: CP
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: P3221
Unit cell:
a: 210.775Å b: 210.775Å c: 84.502Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.199 0.234