PDB 4gms structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Biochemical function:

host cell surface receptor binding

Biological process:

fusion of virus membrane with host plasma membrane

Cellular component:

viral envelope

Sequence domains:

4 more domains

Structure analysis Details

Assembly composition:

hetero dodecamer (preferred)

Assembly name:

Hemagglutinin HA2 chain and IG-light kappa chain and IG-heavy chain (preferred)

PDBe Complex ID:

PDB-CPX-208944 (preferred)

Entry contents:

4 distinct polypeptide molecules

Macromolecules (8 distinct):

Hemagglutinin HA1 chain Chains: A, C, E

Molecule details ›

Chains: A, C, E
Length: 320 amino acids
Theoretical weight: 35.17 KDa
Source organism: Influenza A virus (A/Victoria/3/1975(H3N2))
Expression system: Trichoplusia ni
UniProt:

Canonical: P03435 (Residues: 28-346; Coverage: 58%)

Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1

Hemagglutinin HA2 chain Chains: B, D, F

Molecule details ›

Chains: B, D, F
Length: 176 amino acids
Theoretical weight: 20.23 KDa
Source organism: Influenza A virus (A/Victoria/3/1975(H3N2))
Expression system: Trichoplusia ni
UniProt:

Canonical: P03435 (Residues: 347-522; Coverage: 32%)

Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Fab S139/1 light chain Chains: L, M, N

Molecule details ›

Chains: L, M, N
Length: 214 amino acids
Theoretical weight: 23.77 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni

Structure domains: Immunoglobulins

Fab S139/1 heavy chain Chains: H, I, J

Molecule details ›

Chains: H, I, J
Length: 225 amino acids
Theoretical weight: 24.53 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni

Structure domains: Immunoglobulins