› 4hk0

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212620 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
UCA heavy chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 237 amino acids
Theoretical weight: 25.71 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Ig-like domain-containing protein Chains: B, D
Molecule details ›
Chains: B, D
Length: 214 amino acids
Theoretical weight: 22.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8N355 (Residues: 22-234; Coverage: 97%)
Gene name: IGL@
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P62
Unit cell:
a: 102.004Å b: 102.004Å c: 163.085Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.209 0.206 0.258
Expression system: Homo sapiens

Quick links

Citations

33 review citations

Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies.
Lee et al. (2015)
32 more

12 mentions without citation

Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing.
Mishra et al. (2018)
11 more