4kfz

X-ray diffraction
2.8Å resolution

Crystal structure of LMO2 and anti-LMO2 VH complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero dodecamer
PDBe Complex ID:
PDB-CPX-134593 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Rhombotin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 150 amino acids
Theoretical weight: 17.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25791 (Residues: 9-158; Coverage: 95%)
Gene names: LMO2, RBTN2, RBTNL1, RHOM2, TTG2
Sequence domains: LIM domain
Structure domains: Cysteine Rich Protein
Immunoglobulin heavy variable 3-23 Chains: C, D
Molecule details ›
Chains: C, D
Length: 129 amino acids
Theoretical weight: 14.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01764 (Residues: 16-117; Coverage: 100%)
Gene name: IGHV3-23
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P6
Unit cell:
a: 124.26Å b: 124.26Å c: 81.44Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.24 0.239 0.258
Expression system: Escherichia coli