› 4ljl

X-ray diffraction
2.2Å resolution

Structural insights into the unique single-stranded DNA binding mode of DNA processing protein A from Helicobacter pylori

Released:
DOI: 10.2210/pdb4ljl/pdb
PDB entry 4ljl coloured by chain, front view.
PDB entry 4ljl coloured by chain, side view.
PDB entry 4ljl coloured by chain, top view.
Source organism: Helicobacter pylori 26695
Primary publication:
Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Wang W, Ding J, Zhang Y, Hu Y, Wang DC
OpenAccess logo Nucleic Acids Res 42 3478-91 (2014)
PMID: 24369431

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA processing chain A (DprA) Chains: A, B
Molecule details ›
Chains: A, B
Length: 229 amino acids
Theoretical weight: 25.72 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O25100 (Residues: 5-225; Coverage: 82%)
Gene name: HP_0333
Sequence domains: DNA recombination-mediator protein A
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21212
Unit cell:
a: 171.09Å b: 107.86Å c: 37.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.17 0.213
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

Pathogenesis of Helicobacter pylori infection.
de Bernard et al. (2014)
1 more

1 mention without citation

Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA.
Wang et al. (2014)